| Effect | Detail |
|---|---|
| Assassin’s | +50% damage against humans |
| Automatic | Auto fire mode for laser muskets |
| Berserker’s | More damage the lower your armor resistance, up to +200% |
| Bloodied | More damage the lower your health is |
| Cavalier’s | -15% damage while blocking and sprinting |
| Crippling | +50% more limb damage |
| Enraging | Critical hits cause frenzy |
| Explosive | Exploding bullets do 15 AOE damage |
| Exterminator’s | +50% damage against Mirelurks and bugs |
| Freezing | +10 cryo damage and freeze on critical hit |
| Furious | Increased damage on consecutive hits on same target |
| Ghoul slayer’s | +50% damage against ghouls |
| Hunter’s | +50% damage against animals |
| Incendiary | +15 fire damage |
| Instigating | Double damage if target is at full health |
| Irradiated | +50 radiation damage |
| Junkie’s | Increased damage the more withdrawal effects you are suffering |
| Kneecapper | +20% chance to cripple legs |
| Lucky Weapon | Critical damage doubled and critical meter fills 15% faster |
| Medic’s | Heals target instead of causing damage |
| Mighty | +25% damage |
| Mutant slayer’s | +50% damage against super mutants |
| Never Ending | Ammo capacity will equal total amount available |
| Nimble | +75% faster while aiming down sights |
| Nocturnal | Increased damage at night |
| Penetrating | Ignores 30% of targets damage and energy resistance |
| Plasma infused | +10 energy damage and turns enemies into puddles |
| Poisoner’s | Target is poisoned for 10 seconds |
| Powerful | +25% damage |
| Quickdraw | -25% action point cost |
| Rapid | +25% fire rate and +15% reload rate |
| Relentless | Refill action points on critical hit |
| Sentinel’s | -15% damage while standing and not moving |
| Staggering | Chance to stagger on hit |
| Stalker’s | While not in combat, increases VATS accuracy but costs more action points |
| Troubleshooter’s | +50% damage against robots |
| Two shot | Fires addition projectile, decreases accuracy |
| VATS enhanced | Improved VATS accuracy and -25% action point cost |
| VATS enhanced | -40% action point cost |
| Violent | +25% damage and limb damage with more recoil |
| Wounding | +25 damage from bleeding |